Adenosine-Dependent Vasodilation and the Quest for “Maximal” Hyperemia
نویسندگان
چکیده
منابع مشابه
Adenosine-Dependent Vasodilation and the Quest for "Maximal" Hyperemia: Does Flow Provide an Answer?
With great interest, we read the work of Adjedj and colleagues (1), demonstrating the dose-response curve of intracoronary adenosine for hyperemia, expressed in terms of coronary flow velocity. The authors should be congratulated for this elegant study, which by focusing on the flow response to adenosine has important incremental value over previous studies on the subject. Nonetheless, some con...
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BACKGROUND Maximal hyperemia is the critical prerequisite for fractional flow reserve (FFR) assessment. Despite intravenous (IV) adenosine currently being the recommended approach, intracoronary (IC) administration of adenosine constitutes a valuable alternative in everyday practice. However, it is surprisingly unclear which IC strategy allows the achievement of FFR values that are comparable t...
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15 صفحه اولAdrenergic influence in the coronary circulation of conscious dogs during maximal vasodilation with adenosine.
The coronary arteries receive rich adrenergic innervation. The present study examines the effects of changes in adrenergic activity on the coronary circulation without the complicating influence of autoregulation. Diastolic and mean circumflex coronary artery pressure-flow relations were generated in conscious dogs and were described by their slope and zero-flow, pressure-axis intercept during ...
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ژورنال
عنوان ژورنال: JACC: Cardiovascular Interventions
سال: 2016
ISSN: 1936-8798
DOI: 10.1016/j.jcin.2015.10.030